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US Patent 7655636 Use of A2A adenosine receptor agonists

Patent 7655636 was granted and assigned to Gilead Palo Alto, Inc on February, 2010 by the United States Patent and Trademark Office.

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Current Assignee
‌
Gilead Palo Alto, Inc
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7655636
Date of Patent
February 2, 2010
Patent Application Number
11253322
Date Filed
October 19, 2005
Patent Primary Examiner
‌
Lawrence E Crane
Patent abstract

The present invention relates to methods for producing coronary vasodilation with little peripheral vasodilation by administering doses of a pharmaceutical composition including regadenoson, named (1-{9-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-N-methylcarboxamide, — an adenosine A2A receptor agonist — to a human in an amount sufficient to increase the average coronary peak flow velocity by at least about 16.5 cm/sec.

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