Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Gwong-Jen J. Chang0
Date of Patent
February 16, 2010
0Patent Application Number
105007960
Date Filed
April 4, 2002
0Patent Primary Examiner
Patent abstract
The present invention encompasses isolated nucleic acids containing transcriptional units which encode a signal sequence of one flavivirus and an immunogenic flavivirus antigen of a second flavivirus or of a chimeric immunogenic flavivirus antigen comprising sequence from more than one flavivirus. The invention further encompasses a nucleic acid and protein vaccine and the use of the vaccine to immunize a subject against flavivirus infection. The invention also provides antigens encoded by nucleic acids of the invention, antibodies elicited in response to the antigens and use of the antigens and/or antibodies in detecting flavivirus or diagnosing flavivirus infection.
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