Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Mark A. Gallop0
Laxminarayan Bhat0
Date of Patent
February 16, 2010
Patent Application Number
10893130
Date Filed
July 15, 2004
Patent Primary Examiner
Patent abstract
Disclosed herein are methods for synthesizing 1-(acyloxy)-alkyl prodrug derivatives of drugs through oxidation of 1-acyl-alkyl derivatives of drugs under anhydrous reaction conditions. The methods typically proceed stereospecifically, in high yield, do not require the use of activated intermediates and/or toxic compounds and are readily amenable to scale-up.
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