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US Patent 7666583 Identification of cancer protein biomarkers using proteomic techniques

Patent 7666583 was granted and assigned to Yale University on February, 2010 by the United States Patent and Trademark Office.

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Patent abstract

The claimed invention describes methods to diagnose or aid in the diagnosis of cancer. The claimed methods are based on the identification of biomarkers which are particularly well suited to discriminate between cancer subjects and healthy subjects. These biomarkers were identified using a unique and novel screening method described herein. The biomarkers identified herein can also be used in the prognosis and monitoring of cancer. The invention comprises the use of leptin, prolactin, OPN and IGF-II for diagnosing, prognosis and monitoring of ovarian cancer.

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