Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
February 23, 2010
Patent Application Number
12336995
Date Filed
December 17, 2008
Patent Primary Examiner
Patent abstract
A P4 variant protein that has reduced enzymatic activity and that induces antibody to wild-type P4 protein and/or has good bactericidal activity against non-typable H. influenzae (NTHi) is useful as an active component in an immunogenic composition for humans. Methods of using these proteins, and compositions containing them in combination with additional antigens, are also provided.
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