Patent 7671189 was granted and assigned to Verenium Corporation on March, 2010 by the United States Patent and Trademark Office.
The invention relates to haloalkane dehalogenases and to polynucleotides encoding the haloalkane dehalogenases. In addition methods of designing new dehalogenases and method of use thereof are also provided. The dehalogenases have increased activity and stability at increased pH and temperature.