Patent 7682572 was granted and assigned to Covance on March, 2010 by the United States Patent and Trademark Office.
A tissue microarray includes frozen tissue cores that extend from the top of the tissue microarray to a release. The release is a material from which embedding material of the tissue microarray can easily be removed. A stiffener is used with the release to maintain a flat shape of the release. The tissue cores may be formed from whole (i.e., paraffin-free) frozen tissue. A method and tool for manufacturing the tissue microarray are also disclosed.