A reservoir assembly for a pagewidth printhead cartridge has a fluid distribution molding with priming inlets in fluid communication with fluid channels for supplying printing fluid to a plurality of printhead integrated circuits. The assembly includes a reservoir compartment arranged in fluid communication with the fluid channels via a fluid outlet. The reservoir compartment defines a vent hole to facilitate pressure equalization in the compartment and a bypass fluid path interconnecting the fluid outlet and a well region defined by the compartment. A bypass valve is operatively arranged with respect to the fluid path to facilitate priming the reservoir compartment with printing fluid.