Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
April 13, 2010
Patent Application Number
10802497
Date Filed
March 16, 2004
Patent Primary Examiner
Patent abstract
The invention provide methods and compositions for localized delivery of a vector comprising a therapeutic agent to a specific region of the brain that is overstimulated in neurodegenerative diseases. In particular, the invention provides methods and compositions used to deliver an adeno-associated virus vector (AAV) comprising a nucleotide sequence encoding glutamic acid decarboxylase (GAD) to cells in the hippocampus, subthalamic nucleus of the basal ganglia, mesaphilia and thalamus.
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