Patent 7700732 was granted and assigned to Octapharma on April, 2010 by the United States Patent and Trademark Office.
An albumin containing fraction having a reduced prekallikrein activator (PKA) content and a method of manufacturing same comprising the steps of:(a) reconstitution of paste V (Cohn fractionation),(b) performing a concentration step of the fraction obtained in step (a),(c) heating the fraction obtained in step (b) in a range of from 50° C. to 70° C. for a sufficient time to pasteurize the fraction, and(d) optionally filling of the obtained fraction for use.