US Patent 7705132 Stable polypeptide formulations
Patent 7705132 was granted and assigned to Amgen on April, 2010 by the United States Patent and Trademark Office.
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Patent abstract
The invention provides a formulation including a buffer having a pH less than 6.0, a divalent cation between about 5-200 mM, an excipient comprising a sugar or polyol and an effective amount of a therapeutic polypeptide. Also provided is a method of stabilizing a polypeptide. The method includes contacting a therapeutic polypeptide with a concentration of divalent cation between about 5-150 150 mM in a buffer having a pH less than 6.0 and an excipient comprising a sugar or polyol.
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Patent Inventor Names
Arnold McAuley0
Dirk Chelius0
Douglas Rehder0
Masazumi Matsumura0
Pavel Bondarenko0
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US Patent 07705132 Stable polypeptide formulations US Patent 7705132 Stable polypeptide formulations
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Patent Number
077051320
Patent Number
77051320
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Is a
Current Assignee
Patent Jurisdiction
Patent Number
077051320
Date of Patent
April 27, 2010
0Patent Application Number
119730510
Date Filed
October 5, 2007
0Official Website
Patent Primary Examiner
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US Patent 07705132 Stable polypeptide formulations
Infobox
Is a
Current assignee
Patent jurisdiction
Patent number
07705132
Date of patent
April 27, 2010
Patent application number
11973051
Date Filed
October 5, 2007
Patent primary examiner
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