Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Richard L. Gehant0
Date of Patent
May 11, 2010
Patent Application Number
11537565
Date Filed
September 29, 2006
Patent Primary Examiner
Patent abstract
The invention includes a process for extracting a target protein from Escherichia coli cells that includes lowering the pH of a whole Escherichia coli cell solution to form an acidic solution, disrupting the cells to release the protein into the acidic solution, and separating the cellular debris from the released protein to obtain a protein product enriched in the heterologous target protein. The invention also includes addition of a solubility enhancer.
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