US Patent 7713979 Cycloalkyl lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1

Patent 7713979 was granted and assigned to Eli Lilly and Company on May, 2010 by the United States Patent and Trademark Office.

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Patent

Patent attributes

Current Assignee

Eli Lilly

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

77139790

Patent Inventor Names

Zhaogen Chen0

Ronald Jay Hinklin0

Thomas Daniel Aicher0

Thomas Edward Mabry0

Hongqi Tian0

Jefferson Ray McCowan0

John Gordon Allen0

Leonard Larry Winneroski, Jr.0

...

Date of Patent

May 11, 2010

Patent Application Number

117181110

Date Filed

October 26, 2005

Patent Primary Examiner

‌

Golam M. M. Shameem

Patent abstract

The present invention discloses compounds of Formula I: (I) having 11beta-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as the use of the Formula I and compositions as medicaments to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, Syndrome X, and other conditions associated with hyperglycemia.

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