A magnetic levitation sliding structure is provided for a portable electronic device. The sliding structure includes a first slider member with a guide portion, a second slider member with a receiving portion that mates with the guide portion, a first magnet coupled with the guide portion and having magnetic poles arranged in a direction perpendicular to a sliding direction, and a spaced-apart pair of second magnets coupled with the receiving portion. The first magnet is configured between the spaced-apart pair of second magnets for facilitating relative sliding movement of the first and second slider members. A portable electronic device including the magnetic levitation sliding structure is also provided.