US Patent 7720269 Volumetric characterization using covariance estimation from scale-space hessian matrices

A method for determining a volume of interest in data includes determining fixed-bandwidth estimations of a plurality of analysis bandwidths, wherein the estimation of the fixed-bandwidth comprises, providing an estimate of a mode location of the volume of interest in the data, and determining a covariance of the volume of interest using a local Hessian matrix. The method further includes determining the volume of interest as a most stable fixed-bandwidth estimation across each of the plurality of analysis bandwidths.