A security system with a processor that receives information from multiple sources. The system is illustrated by a network of inspection machines at multiple locations in an airport, such as at check-in desks. These machines provide data to the processor for threat detection processing. The processor provides a central control and data integration point. Centralized control may be used to readily adapt threat detection programs and data integration may allow more accurate or more thorough threat determinations to be made. Moreover, centralized processing of computation intensive operations, such as image reconstruction, may provide for more efficient processor utilization throughout the system, providing a lower total processing cost. Additionally, centralized processing allows for human decision makers to be readily integrated into the system.