Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Xiaojian Sun0
Feng Jiang0
Jie Lin0
Murray Robinson0
Bin Feng0
Date of Patent
June 15, 2010
0Patent Application Number
126453550
Date Filed
December 22, 2009
0Patent Primary Examiner
Patent abstract
A diagnostic method for predicting whether a human tumor will be sensitive or resistant to treatment with tivozanib (AV-951) is disclosed. The method is based on measurement of macrophage content in a tissue sample from a tumor. Measurement of macrophage content can be based on analysis of macrophage marker gene expression, e.g., by RNA analysis or immunohistochemistry.
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