Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Søren Weis Dahl0
John Pedersen0
Marjetka Podobnik0
Sine Larsen0
Anders Kadziola0
Connie Lauritzen0
Dusan Turk0
Igor Stern0
...
Date of Patent
June 15, 2010
Patent Application Number
10363712
Date Filed
September 6, 2001
Patent Primary Examiner
Patent abstract
The present invention relates to structural studies of dipeptidyl peptidase I (DPPI) proteins, modified dipeptidyl peptidase I (DPPI) proteins and DPPI co-complexes. Included in the present invention is a crystal of a dipeptidyl peptidase I (DPPI) and corresponding structural information obtained by X-ray crystallography from rat and human DPPI. In addition, this invention relates to methods for using structure co-ordinates of DDPI, mutants hereof and co-complexes, to design compounds that bind to the active site or accessory binding sites of DPPI and to design improved inhibitors of DPPI or homologues of the enzyme.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
