Patent 7740847 was granted and assigned to APPLIED MOLECULAR EVOLUTION on June, 2010 by the United States Patent and Trademark Office.
The present invention provides humanized anti-CD20 antibodies comprising a human IgG1 Fc region comprising an isoleucine at position 247 and a glutamine at position 339 as well as nucleic acids encoding the antibodies and methods of using the antibodies for treating lymphoma. Furthermore, the invention provides compositions comprising the antibodies and methods of producing them.