Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Marie Dutreix0
Jian-Sheng Sun0
Date of Patent
June 22, 2010
Patent Application Number
12324030
Date Filed
November 26, 2008
Patent Primary Examiner
Patent abstract
The invention relates to compositions and methods for interfering with the DNA repair of double strand breaks (DSBs). The invention discloses novel double-stranded nucleic acid molecules. that act as baits and hijack the holocomplex of enzymes responsible of DNA DSB sensing, signaling and/or repair pathways, in particular the non homologous end joining (NHEJ) pathway of DSB repair.
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