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US Patent 7741446 Fusion antibodies that cross the blood-brain barrier in both directions

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Is a
Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7741446
Date of Patent
June 22, 2010
Patent Application Number
11841623
Date Filed
August 20, 2007
Patent Citations Received
‌
US Patent 12134651 Anti-Ryk antibodies and methods of using the same
0
‌
US Patent 11912778 Methods of engineering transferrin receptor binding polypeptides
0
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US Patent 11965025 Method of treating solid cancers with bispecific interleukin-anti-TCRß molecules
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0
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US Patent 11912750 GDNF fusion polypeptides and methods of use thereof
0
Patent Primary Examiner
‌
Daniel E Kolker
Patent abstract

The invention provides diagnostic and therapeutic macromolecular compositions that cross the blood-brain barrier, in some embodiments in both directions, while allowing their activity to remain substantially intact once across the barrier. Also provided are methods for using such compositions in the diagnosis or treatment of CNS disorders such as Alzheimer's disease.

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