US Patent 7744610 System for closing a tissue structure from inside

A method for closing an aneurysm in a blood vessel may utilize a staple having two or more tines, where those tines are oriented at least partially in the proximal direction. The method may include advancing the staple through the vasculature to a location within the aneurysm, plastically deforming the staple to a splayed configuration, penetrating at least one said tine of the staple in that splayed configuration into tissue in proximity to the neck of the aneurysm, and plastically deforming the staple to a closed configuration to close the aneurysm.