Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael Christopher Montalto0
Cristina Tan Hehir0
Eric Dustin Agdeppa0
Kenneth Michael Fish0
Date of Patent
June 29, 2010
0Patent Application Number
115804930
Date Filed
October 13, 2006
0Patent Primary Examiner
Patent abstract
Provided herein are amyloid-binding assays that simulate in situ brain conditions by combining binders with various A-beta species on mammalian brain tissue. In general the amyloid-binding assays comprise the steps of (a) contacting a mammalian brain tissue sample with at least one A-beta species; (b) applying a putative binder to the brain tissue sample; and (c) determining whether the putative binder binds to the A-beta species.
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