Patent 7749532 was granted and assigned to Supernus Pharmaceuticals, Inc. on July, 2010 by the United States Patent and Trademark Office.
Disclosed are once-daily formulations containing tetracyclines, especially doxycycline. Such formulations are useful, for instance, for the treatment of collagenase destructive enzyme-dependent diseases, such as periodontal disease and acne, and acute and chronic inflammatory disease states, such as rosacea and arthritis.