A bicycle wheel securing structure includes an outer axle, an inner axle, a head member, a lever member, a fixing structure and an adjustment member. The outer axle has a first threaded end and a second end. The inner axle is coupled to the outer axle within an internal bore of the outer axle. The head member is disposed on the inner axle with the lever member operatively mounted to move the head member relative to the inner axle in response to movement of the lever member. The fixing structure is disposed between the outer axle and the inner axle to releasably prevent axial removal of the inner axle from the internal bore of the outer axle. The fixing structure and the adjustment member cooperate together to adjust a final position of the lever member in a rotational direction with respect to the outer axle.