Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael Rosenblum0
Laura K. Shawver0
Date of Patent
July 13, 2010
0Patent Application Number
109641950
Date Filed
October 13, 2004
0Patent Primary Examiner
Patent abstract
Novel immunotoxins and methods of treating neoplastic diseases are provided. More specifically, immunotoxins comprised conjugation of a c-erbB-2 targeting moiety and a cell growth modulator are provided. These immunotoxins specifically and selectively kill tumor cells that over-express the c-erbB-2 protein. The novel immunotoxins would be useful in treating human mammary carcinomas, human ovarian carcinomas, lung carcinomas, gastric tumors, salivary gland adenocarcinomas, and colon adenocarcinomas.
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