Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Philip M. Sass0
Kenneth W. Kinzler0
Luigi Grasso0
Nicholas C. Nicolaides0
Bert Vogelstein0
Date of Patent
July 20, 2010
0Patent Application Number
119304000
Date Filed
October 31, 2007
0Patent Primary Examiner
Patent abstract
Yeast cells are mutagenized to obtain desirable mutants. Mutagenesis is mediated by a defective mismatch repair system which can be enhanced using conventional exogenously applied mutagens. Yeast cells with the defective mismatch repair system are hypermutable, but after selection of desired mutant yeast strains, they can be rendered genetically stable by restoring the mismatch repair system to proper functionality.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
