Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Robert W. Finberg0
Evelyn A. Kurt-Jones0
Date of Patent
July 20, 2010
0Patent Application Number
121346070
Date Filed
June 6, 2008
0Patent Primary Examiner
Patent abstract
It has been found that Toll-like receptor 1 and Toll-like receptor 2 (TLR2) physically interact. Antibodies that specifically bind to TLR2 and selectively inhibit induction of cytokines are also described. The invention relates to specific antibodies that selectively bind to TLR2, and to methods of identifying compounds that selectively interfere with signaling through TLR1/TLR2 complexes.
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