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US Patent 7763254 Human immunodeficiency virus integrase-LEDGF p75 isoform protein-protein interactions

Patent 7763254 was granted and assigned to CellVir on July, 2010 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to protein-protein interactions involved in AIDS. More specifically, the present invention relates to complexes of polypeptides or polynucleotides encoding the polypeptides, fragments of the polypeptides, antibodies to the complexes, Selected Interacting Domains (SID®) which are identified due to the protein-protein interactions, methods for screening drugs for agents which modulate the interaction of proteins and pharmaceutical compositions that are capable of modulating the protein-protein interactions.

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