Patent 7767880 was granted and assigned to PHYLONIX PHARMACEUTICALS, INC. on August, 2010 by the United States Patent and Trademark Office.
The present invention provides methods of screening an agent for activity using teleosts. Methods of screening an agent for angiogenesis activity, toxic activity and an effect cell death activity in teleosts are provided. Methods of screening an agent for an activity in the brain or central nervous system in zebrafish are provided. The invention further provides high throughput methods of screening agents in multi-well plates.