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US Patent 7771997 Enhanced expression and stability regions

Patent 7771997 was granted and assigned to Regeneron Pharmaceuticals, Inc. on August, 2010 by the United States Patent and Trademark Office.

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Patent abstract

Expression-enhancing nucleotide sequences for expression in eukaryotic systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Enhanced expression and stability regions (EESYRs) are provided for expression of a gene of interest in a eukaryotic cell. Chromosomal loci, sequences, and vectors are provided for enhanced and stable expression of genes in eukaryotic cells.

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