Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
August 17, 2010
Patent Application Number
11179008
Date Filed
July 8, 2005
Patent Citations Received
Patent Primary Examiner
Patent abstract
Methods and compositions are provided for extending the clinical utility of IFN-α in the treatment of a variety of viral and proliferative disorders. Among other aspects, the invention provides methods which increase the efficacy of IFN-α treatment and reduce IFN-α treatment-related side effects. In addition, methods are provided for supporting the survival and for activating natural interferon producing cells (IPCs) in vitro without exogenous IL-3 or GM-CSF. The invention is based on the discovery that certain CpG and non-CpG ISNAs promote survival and stimulation of IPCs.
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