Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Helena S. Mancebo0
Samuel X. Li0
Jianfu L. Wang0
Jeng-Horng Her0
Date of Patent
August 24, 2010
0Patent Application Number
115298260
Date Filed
September 29, 2006
0Patent Primary Examiner
Patent abstract
The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.
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