Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Steven J. Norris0
Jerrilyn K. Howell0
Jing-Ren Zhang0
John M. Hardham0
Alan G. Barbour0
George M. Weinstock0
Date of Patent
August 31, 2010
0Patent Application Number
115011660
Date Filed
August 7, 2006
0Patent Primary Examiner
Patent abstract
The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.
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