Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Timothy J. O'Brien0
Date of Patent
August 31, 2010
0Patent Application Number
110127870
Date Filed
December 15, 2004
0Patent Primary Examiner
Patent abstract
The disclosed nucleic acid primer sets, used in combination with quantitative amplification (PCR) of tissue cDNA, can indicate the presence of specific proteases in a tissue sample. Specifically, the present invention relates to expression of PUMP-1 protease (matrix metalloprotease 7). The detected proteases are themselves specifically over-expressed in certain cancers, and their presence may serve for early detection of associated ovarian and other malignancies, and for the design of interactive therapies for cancer treatment.
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