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Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Andrew Wilke0
Anil Rajaram Oroskar0
Anthony Charles Grabski0
Herbert Edmund Paaren0
Joerg Werner Baier0
Robert Charles Mierendorf0
Date of Patent
September 7, 2010
0Patent Application Number
118479830
Date Filed
August 30, 2007
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides devices and methods for micro-scale simulated moving bed chromatography (SMB) for continuous preparation of analytic quantities of highly pure fractions of target molecules. The present apparatus and method of the invention is adapted in a preferred embodiment to separations by affinity chromatography involving three discontinuous liquid flow loops. An alternative embodiment of affinity chromatography utilizes standard SMB operating under isocratic conditions.
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