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US Patent 7790655 Cell display of antibody libraries

Patent 7790655 was granted and assigned to MedImmune on September, 2010 by the United States Patent and Trademark Office.

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Changshou Gao0

Herren Wu0

Date of Patent

September 7, 2010

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Patent Application Number

115800050

Date Filed

October 13, 2006

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Patent Citations Received

US Patent 11851497 CD137 antibodies and tumor antigen-targeting antibodies and uses thereof

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US Patent 11976381 Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts

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US Patent 11970538 Multispecific binding constructs against checkpoint molecules and uses thereof

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US Patent 11752207 Agonist antibodies that bind human CD137 and uses thereof

Patent Primary Examiner

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Patent abstract

The present invention relates to a viral vector encoding for a library of antibodies or antibody fragments that are displayed on the cell membrane when expressed in a cell. The present invention provides cells comprising the viral vector nucleic acids and methods of screening the libraries for antibodies or antibody fragments with desired characteristics.

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