US Patent 7811790 Polymyxin synthetase and gene cluster thereof

Patent 7811790 was granted and assigned to Korea Research Institute of Bioscience and Biotechnology on October, 2010 by the United States Patent and Trademark Office.

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Patent

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Current Assignee

‌

Korea Research Institute of Bioscience and Biotechnology

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

78117900

Patent Inventor Names

Yon Kyoung Park0

Seung-Hwan Park0

Soo-Keun Choi0

Soo-Young Park0

Choong-Min Ryu0

ChoongHwan Lee0

Heayoung Jeong0

Jihyun F. Kim0

...

Date of Patent

October 12, 2010

Patent Application Number

120967890

Date Filed

November 8, 2006

Patent Primary Examiner

Nashaat T. Nashed

Patent abstract

The present invention relates to a polymyxin synthetase isolated from Gram-positive Paenibacillus sp. and a gene cluster encoding the same, more precisely a polymyxin synthetase isolated from Paenibacillus polymyxa E681, a gene cluster encoding thereof and a preparation method of polymyxin or its derivatives using the gene cluster. The polymyxin synthetase of the present invention can be effectively used for the increase of productivity of polymyxin and the development of a novel antibiotic.

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