A disposable stethoscope cover that covers at least the surface of the diaphragm is disclosed. The cover contacts a patient during use and reduces transmittal of microorganisms. The cover is in the form of a flexible sheet having a top and a bottom surface. The sheet has an adhesive material on a portion of the surface thereof that secures the sheet to the surface of the diaphragm. The sheet further includes at least one wing extending from the sheet. The wing has an adhesive on at least one surface thereof for securing the wing to the sheet when the wing is folded over at least a portion of a tube section of the stethoscope.