Patent 7824462 was granted and assigned to Purdue Research Foundation on November, 2010 by the United States Patent and Trademark Office.
A composition for use as a prosthetic biomaterial and associated method. The biomaterial exhibits cytocompatibility, mechanical functionality and osteoblast adhesion between the implant and interfacing surface. The biomaterial is metallic, has a grain size less than about 500 nanometers and has a surface roughness of less than about 800 nm rms.