A universal pill splitter as an upper pill splitter body with a cutting blade affixed to a lower side of the upper body and a lower body rotating affixed to the upper body, with two pill stops affixed to the upper side of the lower body, with a slide slidingly affixing to the lower body, wherein the slide further contains two pill guides at either side of a slot centrally located in the slide body, so that when a pill is place on the lower body against the pill stops and the slide is pushed forward so that it engages the pill, pressing it securely against the pill stops, the pill may be split by rotating the upper body toward the lower body, thereby driving the cutting blade against a top of the pill.