Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Alexandra Treschow0
Sirac Dilber0
Alar Aints0
Date of Patent
November 9, 2010
0Patent Application Number
126265790
Date Filed
November 25, 2009
0Patent Primary Examiner
Patent abstract
A recombinant Na+, K+-ATPase α1-subunit protein resistant to cardiac glycosides, e.g. oubain, is disclosed, as well as methods for its production and use. The resistance to cardiac glycosides are obtained by alterations in the region situated between and including the amino acids 65-133. Such recombinant protein and nucleic acid constructs expressing the same are useful as selection markers in gene therapy and research applications.
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