Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Joseph T. Chang0
Ann-Joy Cheng0
Ching-Chi Chiu0
Date of Patent
November 9, 2010
0Patent Application Number
121749970
Date Filed
July 17, 2008
0Patent Primary Examiner
Patent abstract
The present invention discloses a specific GRP78 expression-inhibition RNAi sequence, a medicine thereof and a method thereof, wherein an RNAi sequence 5′-AAGGATGGTTAATGATGCTGAGAA-3′ complementary to GRP78 forms a special hair-pin structure inside cancer cells to specifically and effectively inhibit GRP78 expression and then inhibit the canceration process, including the growth, migration, invasion, and metastasis of cancer.
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