US Patent 7831293 Method of defining a biological target for treatment

A method of defining a biological target for treatment in which image detectable markers are placed at and correlated to the location or locations of tissue biopsy. By obtaining pathological analysis of the biopsy tissue specimens and correlating the analysis to the corresponding marker locations, the definitive pathological analysis of the target tissue at the marker locations can be correlated to corresponding locations on a functional image of the target tissue. The correlation of the marker locations and pathology to the corresponding locations on a functional image can then be used to prescribe and apply modulated therapy to the target tissue.