Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Carolyn A. Haller0
Elliot L. Chaikof0
Chrystelle S. Cazalis0
Date of Patent
November 16, 2010
Patent Application Number
10598149
Date Filed
February 22, 2005
Patent Citations Received
Patent Primary Examiner
Patent abstract
The transmembrane human protein thrombomodulin (TM), as a critical regulator of the protein C pathway, represents the major anticoagulant mechanism that is operative in both normal and injured blood vessels under physiologic conditions in vivo. Compositions and methods are disclosed relating to thrombomodulin derivatives and conjugates, including methods for site-specific pegylation and compositions of a truncated thrombomodulin derivative.
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