Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
David J. Glass0
Thomas J. Daly0
Nicholas J. Papadopoulos0
George D. Yancopoulos0
Date of Patent
November 23, 2010
Patent Application Number
12134301
Date Filed
June 6, 2008
Patent Citations Received
Patent Primary Examiner
Patent abstract
A fusion protein comprising at least one IGF1 variant component and a fusion component (F), and, optionally, a signal sequence, exhibiting improved stability relative to the native IGF1 or IGF2 polypeptide. The fusion component (F) may be a multimerizing component, a targeting ligand, or another active or therapeutic compound. IGF1 variants were shown to have improved ability to induce skeletal muscle hypertrophy relative to native IGF1.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
