US Patent 7838023 Furoxan compounds, compositions and methods of use
Patent 7838023 was granted and assigned to Nitromed on November, 2010 by the United States Patent and Trademark Office.
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The invention provides novel furoxan compounds, or pharmaceutically acceptable salts thereof, and novel compositions comprising at least one compound, and, optionally, at least one nitric oxide enhancing compound and/or at least one therapeutic agent. The compounds and compositions of the invention can also be bound to a matrix. The invention also provides methods for (a) treating cardiovascular diseases; (b) inhibiting platelet aggregation and platelet adhesion caused by the exposure of blood to a medical device; (c) treating pathological conditions resulting from abnormal cell proliferation; (d) treating transplantation rejections, (e) treating autoimmune, inflammatory, proliferative, hyperproliferative or vascular diseases; (f) reducing scar tissue or for inhibiting wound contraction; (g) treating diseases resulting from oxidative stress; (h) treating endothelial dysfunctions; and (j) treating diseases caused by endothelial dysfunctions.
US Patent 07838023 Furoxan compounds, compositions and methods of use US Patent 7838023 Furoxan compounds, compositions and methods of use
US Patent 07838023 Furoxan compounds, compositions and methods of use
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