An airline chair cover system includes an airline chair that includes a seat portion and a backrest attached to and extending upwardly from the seat portion. A flexible panel is removably positioned on top of the chair to cover the seat portion and the backrest. The panel includes an upper edge, a lower edge and a pair of lateral edges. A peripheral wall is attached to and is coextensive with each of the upper edge, the lower edge and the pair of lateral edges. The peripheral wall has a perimeter edge positioned distal to the panel. The peripheral wall is removably positioned on a top edge of the backrest, a front edge of the portion and lateral sides of the backrest and the seat portion. The panel covers an upper surface of the backrest and the seat portion.