A fastener driving device includes various interconnected systems within a device housing for efficiently regulating and transferring compressed gas provided by user-replaceable cartridges to drive a fastener securely into a workpiece. An improved cartridge containment system is provided for loading and securing compressed gas cartridges. An improved gas management system is provided, including an improved multi-function regulator, for managing gas flow. An improved valve system is provided for controlling gas flow, including an improved valve module. An improved drive system is provided for efficiently using compressed gas to drive fasteners.