Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
John R. Carney0
Gary W. Ashley0
Hugo Menzella0
Janice Lau Wee0
Date of Patent
December 21, 2010
0Patent Application Number
120110680
Date Filed
January 23, 2008
0Patent Primary Examiner
Patent abstract
Macrolactams are made by feeding aromatic amino acids as replacement starter units to a mutant strain of the geldanamycin-producing microorganism Streptomyces hygroscopicus var. geldanus NRRL 3602, wherein the gene cluster encoding enzymes for the biosynthesis of the natural starter unit 3-amino-5-hydroxybenzoic acid has been deleted.
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